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Cardio Aspirin

22:27
CARDIOASPIRIN®
ACETYL SALICYLIC ACID
100 mg
ENTERIC COATED TABLET


Composition;
Each enteric-coated tablet Cardio Aspirin contains acetyl salicylic acid 100 mg.

Pharmacodynamic Properties;
The biochemical mode of action of acetylsalicylic acid on the inhibition of platelet aggregation is therefore based on:
  1. An Irreversible inhibition of cyclo-oxygenase in the platelets, and
  2. A reversible inhibition of cyclo-oxygenase in the vessel wall.

Indications:

  • To reduce the risk of further coronary thrombosis during recovery phase from myocardial infarction (re-infarction prophylaxis)
  • To lower the risk of morbidity and/or MI attack (myocardial infarct) in patients with history of MI or unstable angina pectoris
  • To prevent thrombosis (re-occlusion prophylaxis) after aorto-coronary bypass
  • To reduce the risk of recurrent transient ischaemic attack (TIA) and stroke In patients with TIA.

Note;
Due to possibility or Reye's syndrome, the use of enteric-coated tablet Cardio Aspirin 100 in children and adults with fever should only be on physician's recommendation or if other measures have been proven ineffective.

Dosage:
Unless specific instruction from the doctor, the recommended dosages are as follows:

  • Usually 100 mg daily
  • Reducing the risk of morbidity and mortality in patients with previous myocardial infarction: A daily dose of 100 mg to 300 mg Is currently recommended
  • Reducing the risk of transient ischaemic attacks (TIA) and stroke in patients with TIA: A daily dose of 100 mg to 300 mg is currently recommended.

Administration:
Tablets should be swallowed with liquid, preferably before meals with plenty of liquid.

Contraindications:
Enteric-coated tablet Cardio Aspirin 100 must not be given to patients with gastric or duodenal ulcers and in patients with tendency of pathologic haemorrhagic disorders, patients with other bleeding disorders, and hypersensitivity to Acetosal.

Warnings and Precautions:

  • Medicinal products containing acetylsalicylic acid should be used in children and adolescents with febrile diseases only after careful risk-benefit-evaluation because of the possibility of Reye's syndrome, a rare but serious illness.
  • Due not use in pregnant women and nursing mothers unless on a doctor's advice
  • Cardio Aspirin should not be used in patients with severe hepatic damage, hypo-prothrombinemia or vitamin K deficiency.
  • Discontinue its use in case of tinnitus, impaired hearing, or dizziness.
  • Consult a doctor immediately in case of persisting gastric Irritation.
  • Cardio Aspirin should not be used in long-term treatment or in high doses without prior consultation with a doctor.
  • Consultation with a doctor is required when enteric-coated tablet Aspirin 100 is to be given to patients also receiving anticoagulant (e.g. coumarin derivatives and heparin); patients with glucose-6-phosphate-dehydrogynase deficiency: asthmatic patients; patients hypersensitive to salicylates. other anti-inflammatory/anti -rheumatic agents, or other allergenic agents' patients with chronic or recurrent gastric or duodenal symptoms; patients with kidney dysfunction; and pregnant women, particularly in the last trimester.

Note;
Patients with asthma, hay fever, swelling of nasal mucosa (nasal polyp), or patients with chronic respiratory infection (especially when accompanied with signs of hay fever) and patients hypersensitive to all kind of analgesic and anti-rheumatic agents are at risk of asthmatic attack when using enteric-coated tablet Aspirin 100 (same analgesic/analgesic intolerance). Therefore, they must be consulted with a doctor before using this drug. This also apply for patients allergic to other agents, e.g. which are causing skin reaction, itchy, or urticaria.

Adverse reactions:
The following adverse reactions may occur: gastric pain, burning sensation, nausea gastro intestinal bleeding; hypersensitivity reactions (dyspnea attach, skin reaction) may rarely occur; lowering of platelet count (trombocytopenia) may occur; reversible increase of liver enzymes levels in prolonged use of high doses.

Note:
In rare case, gastric bleeding may occur in prolonged and long-termed use. Doctor must be immediately informed If black stool is observed. In particular cases, anemia may occur in long-term use of enteric-coated tablet Aspirin 100 due to gastrointestinal micro-bleeding Dizziness and tinnitus may be the signs of over-dosage, particularly In children and elderly. If this is the case, doctor must be informed. The level of liver enzyme (trans-aminase) may increase if the recommended dose is exceeded.

Drug Interactions:
The following may be aggravated:

  • Effects of anticoagulant (e.g. coumarin derivatives and heparin)
  • Risk of gastrointestinal bleeding in concomitant use with corticosteroids and alcohol
  • Favourable and unfavourable effects of all analgesic and non-steroidal anti-rheumatic agents
  • Effects of hypoglycemic agents (sulphonylurea)
  • Adverse reactions of methotrexates.

Effects of spironolactone, furosemide, and uricosuric antipodagnic may be reduced and, therefore, concomitant use with these drugs should be avoided except on doctor's recommendation.

Storage:
Store below 30°C.

Presentation:
Box of 3 blisters @ 10 tablets.
Made by Bayer HealthCare AG , Germany for Bayer Consumer Care AG, Switzerland.
Imported by PT Bayer Indonesia, Jakarta
Reg. No.: DKI9451600515A1

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