Sunday, January 31, 2010


(Nystatin and Zinc Oxide)

Each gram Myco-Z® ointment contains 100,000 units of nystatin and 200 mg of zinc oxide in a perfumed Plastibase®, an emollient and protective vehicle.

Nystatin is an antifungal antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeast and yeast like fungi. It probably acts by binding to sterols in the cell membrane of the fungus with a resultant change in membrane permeability allowing leakage of intracellular components.
Nystatin is a polyene antibiotic of undetermined structural formula that is obtained from Streptomyces noursei, and is the first well tolerated antifungal antibiotic of dependable efficacy for the treatment of cutaneous, oral and intestinal infections caused by Candida (Monilia) albicans and other Candida species. It exhibits no appreciable activity against bacteria.

Nystatin provides therapy for all localized forms of candidiasis.
Symptomatic relief is rapid, often occurring within 24 to 72 hours after the initiation of treatment.
Cure is effected both clinically and mycologically in most cases of localized candidiasis.

Zinc oxide is applied externally as a mild astringent for the skin, as a soothing and protective application in eczema and as a protective to slight excoriations.

Myco-Z® ointment is indicated in the treatment of cutaneous mycotic infections caused by Candida (Monilia) albicans. If the organism is the primary cause of infection, such dermatologic conditions as intertrigo(submammary, inguinal and perineal), paronychia, interdigital mycosis, 'diaper rash' and other cutaneous lesions can be expected to respond.

MYCO-Z® ointment is contraindicated in patients with known hypersensitivity to these components.

Nystatin is virtually nontoxic and nonsensitizing. Myco-Z® ointment is well tolerated by all age groups including debilitated infants, even on prolonged administration. If irritation on topical application should occur, discontinue medication.

Since absorption of nystatin from the gastro-intestinal tract is negligible, accidental ingestion causes no systemic toxicity.

The ointment should be applied liberally to the affected areas two to four times daily, until healing is complete.

Myco-Z® ointment is supplied in tubes of 10 grams.

Store below 30°C. Avoid freezing

Reg. No.: DKL 9024402730 A1

Manufactured by
PT Bristol-Myers Squibb IndonesiaTbk
Under authority of
Bristol-Myers Squibb Co.,
Princeton, New Jersey, U.S.A.


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