Skin Ointment, powder, and Eye Ointment

Each gram of NEBACETIN® contains:
  • 5 mg of neomycin sulphate (equivalent to 2.244 IU of neomycin base).
  • 250 IU of bacitracin.
NEBACETIN® is a combination between antibiotics - neomycin and bacitracin. Research and mechanism show that bacteria cells attacked/destroyed with 2 ways, bacitracin delaying the biosinthesis of cell's wall and neomycin destroy genetic code and synthesis sequel of protein and germ. Hence, NEBACETIN® works
Practical, NEBACETIN® is not absorbed by skin neither mucous, so far topical use it is acceptable in high dose. Using NEBACETIN® in high dose at the ulcer can prevent growth of resistant bacteria.
Mechanism of NEBACETIN® antibiotic can not be block by blood plasma, pus neither necrotic tissue.
Basically, NEBACETIN® indicated for all local skin and mucus infection.

Nebacetin Ointment and Powder:
Superficial bacterial infection of the skin, such as impetigo, varicose ulcers, pressures sores, trophic ulcers and burn.

Nebacetin Eye Ointment:
  • Ophtalmology
    Acute and chronic conjungtivitis, acute and chronic keratitis, kerato - konjungtivitis, dakriosistitis, cornea ulkus, peripheral cornea infiltrate, prevent and cure infection before and after eye surgery.
NEBACETIN® Ointment and Powder:
  • Administration and dosage adults:
    Before use, the area for application should be cleaned gently.
    Debris such as pus or crusts should be removed from the affected area. A thin film of the ointment/a ligh dusting of the powder should be applied to the affected area up to three times/day depending on the clinical condition. Treatment should not be continued for more 7 days without medical supervision.
  • Dosage in children:
    The adults dose is suitable for use in older children, however in infants dosage should be reduced. A possibility of increased absorption exists in very young children, thus ointment/powder is not recommended for use in neonatus.
  • Dosage in renal impairment:
    Dosage should be reduced in patients with reduced renal function.
NEBACETIN® Eye Ointment:
  • Recommended using eye ointment several times a day (2-3 times) into conjunctiva saccus until the sympton dissapears. Basis of the eye ointment has good local tolerance to conjunctiva.
  • Caution should be exercised so that the recommanded dosage is not exceeded.
  • Following significant systemic absorption, amynoglycoside such as neomycin can cause irreversible ototoxicity (and exacerbate existing partial nerve deafness); both neomycin sulphate and bacitracin have nephrotoxic potential.
  • After a treatment course, administration should not be repeated for at least three months.
  • In neonatus and infants, absorption by immature skin may be enhanced and renal function may be immature.
  • In renal impairment the plasma clearance of neomycin is reduced, this is associated with an increased risk of ototoxicity, therefore, a reduction in dose should be made that relates to the degree of renal impairment.
  • As with other antibacterial preparations, prolonged use may result in overgrowth by non-suspectible organism including fungi.
  • Concurrent administration of other amynoglycosides is not recommended.
  • In patients who have demonstrated allergic hypersensitivity to the product or any of its constituents, or to cross-sensitising substances such as framycetin, kanamycin, gentamycin and other related antibiotics.
  • Patients with any degree of nerve deafness in circumstances in which significant systemic absorption could occur.
  • The incidence of allergic hypersensitivity to neomycin sulphate in the general population is low. However, there is an increased incidence of sensitivity to neomycin in certain selected groups
    of patients in dermatological practice particularly those with venous stasis eczema and ulceration.
  • Allergic hypersensitivity to neomycin following topical application may manifest it self as a reddening and scalling of the effected skin, as an eczematous exacerbation of the lesion, or as a failure of the lesion to heal.
  • Allergic hypersensitivity following application of bacitracin has been reported but is rare.
  • Anaphylactic reactions following the topical administration of bacitracin have been reported but are rare.
Following significant systemic absorption, neomycin sulphate can intensify and prolong the respiratory depressant effect of neuromuscular blocking agent.

Tube of 5 g
Bottle of 5 g
NEBACETIN® Eye Ointment
Tube of 2,5 g
No. Reg.DKL7221603431A1


Store in a cool and dry place

Manufactured by:

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