Thiamine Mononitrate + Pyridoxol HCl + Cyanocobalamin
Neurotropic vitamins
Composition
Each sugar-coated tablet contains :
| Vitamin B1 (Thiamine Mononitrate) | 100 | mg |
| Vitamin B6 (Pyridoxol Hydrochloride) | 100 | mg |
| Vitamin B12 | 5000 | mcg |
Mode of action
Vitamin B1 functions in carbohydrate metabolism as a coenzyme in the decarboxylation of α-keto acids. In human body vitamin B6 will be transferred to pyridoxal phosphate and pyridoxamine phosphate which are involved in protein and amino acids metabolism.
Vitamin B12 is essential in nucleic acid synthesis and for cell growth and replication and maintaining the integrity of nervous tissue.
Indications
In the treatment of Vitamin B1, B6 and B12 deficiency in case of beri-beri and polyneuritis.
Dosage and administration
1 tablet daily after meals. In more severe cases, the dose can be increased at the discretion of the physician.
Drug interaction
Decreases the effect of levodopa.
Presentation
Box of 10 x 10 sugar-coated tablets in blister
Box of 25 x 10 sugar-coated tablets in blister
Storage
Store in a dry place, below 25°C
Manufactured by
PT. Merck Tbk., Jakarta
under licence from
Merck KGaA, Germany
Reg.No.: DBL 9615806416 A1
Neurobion® 500 Tablet
Thiamine Mononitrate + Pyridoxol HCl + Cyanocobalamin
Vitamin Neurotropik
Komposisi
Tiap salut gula mengandung :
| Vitamin B1 (Thiamine Mononitrate) | 100 | mg |
| Vitamin B6 (Pyridoxol Hydrochloride) | 100 | mg |
| Vitamin B12 | 5000 | mcg |
Cara kerja
Vitamin B1 berperan sebagai koenzim pada dekarboksilasi asam α-keto dan berperan dalam metabolisme karbohidrat. Vitamin B6 di dalam tubuh berubah menjadi piridoksal fosfat dan piridoksamin fosfat yang dapat membantu dalam metabolisme protein dan asam amino. Vitamin B12 berperan dalam sintesa asam nukleat dan berpengaruh pada pematangan sel dan memelihara integritas jaringan saraf.
Indikasi
Untuk pengobatan kekurangan Vitamin B1, B6 dan B12 seperti pada beri-beri dan polineuritis.
Takaran pemakaian
1 tablet sehari sesudah makan. Dalam keadaan tertentu dosis dapat ditingkatkan sesuai petunjuk dokter.
Interaksi obat
Mengurangi efek levodopa.
Kemasan
Kotak berisi 10 x 10 tablet salut gula dalam blister
Kotak berisi 25 x 10 tablet salut gula dalam blister
Penyimpanan
Simpanlah di tempat yang kering di bawah 25°C
Dibuat oleh
PT. Merck Tbk., Jakarta
dengan lisensi
Merck KGaA, Jerman
No. Reg. : DBL 9615806416 A1
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